Twenty-five people have been hurt after two trains carrying a total of 238 passengers crashed near the French city of Pau.
A national TGV service heading for Paris hit a local train during the evening commute in the town of Deguin, Pyrenees-Atlantiques prefectural spokesman Patrice Abbadie said.
Nine of the injuries are serious, but they are not though to be life-threatening, he added.
Emergency services including ambulances, helicopters and fire engines were sent to the scene.
Reports suggest the high-speed TGV had stopped and was starting up again when the crash took place.
The cause is not clear, and the train operators have launched an investigation.